During the ISBM 2020 online conference (iscb.org), the creator of Nextflow, Paolo Di Tommaso, introduced the next iteration of Nextflow: DSL2. To quickly recap Nextflow, it’s a framework languange that simplifies the creation of scalable workflows for researchers and developers, using a Groovy-based scripting. It manages tasks across diverse computing environments, ensuring reproducibility and scalability. […]
Continue Reading...
Introduction Today, we will continue our journey into the current state-of-the-art of bioinformatics tools that make use of nVidia’s CUDA API. I will discuss specific bioinformatics problems, the default tools that are used in the industry and the possible Graphics Processor (GPU) based alternatives. If you want to read more about the history and purpose […]
Continue Reading...Introduction As most readers of this blog will know, bioinformatics has always been a data-heavy field of research. Many computational problems within bioinformatics can scale up to the sky, from protein folding to calculating homology in sequences. But the real motherload of repetitive data was unleashed on the bioinformatics community when Next Generation Sequencing (NGS) […]
Continue Reading...
When Seven Bridges was conceived, a bioinformatics framework with this in mind didn’t exist yet. So, as those things go, the developers at Seven Bridges made their own language, Rabix, which they release as a beta to the public in 2017.
Continue Reading...
Recently I visited the DTL Programmers Meeting, where I had a discussion with members of the SASC bioinformatics development group. For them, bioinformatics pipelines are more about scalibilty and manageablity, not about user-friendliness or readability. They opted for Cromwell, a framework language maintained by the Broad Institute.
Continue Reading...
One of the biggest changes within the field of bioinformatics is the rise of the framework. In part four, I will focus on Nextflow, the framework build for scaling.
Continue Reading...