Tag Archives: GATK

The story of NVIDIA Parabricks

Introduction NVIDIA Parabricks is a cutting-edge genomic analysis platform that uses GPU acceleration to dramatically reduce the time required for computational tasks in next-generation sequencing (NGS) workflows. Tailored for applications in precision medicine, genomics research, and healthcare, Parabricks accelerates essential bioinformatics tools like the Genome Analysis Toolkit (GATK) for tasks such as variant calling, alignment, […]

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nVidia CUDA Bioinformatics: BarraCUDA

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Introduction Today, we will continue our journey into the current state-of-the-art of bioinformatics tools that make use of nVidia’s CUDA API. I will discuss specific bioinformatics problems, the default tools that are used in the industry and the possible Graphics Processor (GPU) based alternatives. If you want to read more about the history and purpose […]

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Bioinformatics Frameworks Part 5: Cromwell and WDL

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Recently I visited the DTL Programmers Meeting, where I had a discussion with members of the SASC bioinformatics development group. For them, bioinformatics pipelines are more about scalibilty and manageablity, not about user-friendliness or readability. They opted for Cromwell, a framework language maintained by the Broad Institute.

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