Tag Archives: snp

Bioinformatics Frameworks Part 5: Cromwell and WDL

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Recently I visited the DTL Programmers Meeting, where I had a discussion with members of the SASC bioinformatics development group. For them, bioinformatics pipelines are more about scalibilty and manageablity, not about user-friendliness or readability. They opted for Cromwell, a framework language maintained by the Broad Institute.

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Bioinformatics Frameworks Part 1: Bash and Make

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One of the biggest changes within the field of bioinformatics is the rise of the framework. Frameworks are the professionalization of analysis pipelines, constructed with software development and data science in mind. With this series of blogs I will discuss a few that have crossed my path, and try to explain the essence of their design philosophy. It will not be a straight forward choice to pick the framework that suits your workflow best, but I hope these posts will help. Part 1 discusses the precursors of frameworks: Bash and Make.

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